| abstract |
The present invention relates to a therapeutic agent for treatment of disorder of lipid metabolism comprising TCF-II as an effective ingredient. The therapeutic agent of the present invention is useful for treatment of disorder of lipid metabolism caused by diabetes, endocrinological diseases, such as thyroid dysfunction and adrenal dysfunction, chronic metabolism disorder, chronic renal failure including nephrosis, uremia, cancer, dyscrasia, adverted effects of antitumor agents, gastrointestinal (including hepatic and pancreatic) impairment and so on. Hypercholesterolemia, hypolipidemia or hypo-high-density-lipoproteinemia is exemplified as a disorder of lipid metabolism. The therapeutic agent of the present invention normalizes not only hyperlipidemia but also hypolipidemia. In addition, it improves fatty liver. |