http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9619500-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_916075766043ce900399a4c2eee9f054 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-92 |
filingDate | 1995-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96694c35740a584eab21654a415f3310 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ae7a190cdf2d4f9a89456e93e48f398 |
publicationDate | 1996-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-9619500-A1 |
titleOfInvention | METHODS AND MATERIALS FOR THE IMMUNOASSAY OF APOLIPOPROTEIN(a) AND LIPOPROTEIN(a) |
abstract | The present invention relates to monoclonal antibodies and a method for the quantification of apolipoprotein(a) and lipoprotein(a) present in human body fluids. The method is not sensitive to the presence of plasminogen or the apo(a) kringle 4 repeats. The assay involves the addition of the test sample to an immobilized anti-apo(a) antibody and forming a first immobilized complex of apolipoprotein(a)/anti-apo(a) first antibody, contacting first immune complex with an anti-apo(a) monoclonal antibody specific for apo(a) with non crossreactivity to plasminogen and which does not identify the kringle 4 type 2 apo(a) repeats and thereafter quantitating apo(a) based on the amount of bound anti-apo(a) monoclonal antibody. Immobilized goat or rabbit anti-human apo(a) antibody can be employed as the first capture antibody and the mouse anti-apo(a) monoclonal antibody as second antibody. The amount of anti-apo(a) monoclonal antibody bound is quantitated through binding of a third antibody enzyme conjugant, e.g., goat anti-mouse antibody/horseradish peroxidase (HRP) conjugate, followed by reaction with a suitable substrate such as o-phenylenediamine dihydrochloride. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3032258-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3913367-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10539580-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10330690-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016069639-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0857973-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0857973-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014005065-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010078411-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6210906-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9936784-A1 |
priorityDate | 1994-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 117.