| abstract |
Compounds of formula (I) in which R?1 and R2¿, which may be the same or different, is each selected from hydrogen, halogen or C¿(1-8)?alkyl; R?3¿ is aryl or arylC¿(1-4)?alkyl which may be optionally substituted; X is a linker group; Y is an optionally substituted aryl group; and n is 0, 1 or 2; are inhibitors of the enzyme Lp-PLA2 and thereof of use in treating atherosclerosis. |