Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_74b27499a430ff8ded1049ba4dee2c52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39ae5c8af0bf0b5a665860faed373b3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_808ff4b12532bd55d0b4b92adf5c283b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f0dd3924d7cfdab70de77be9d041a39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d50e56bff3ce8944f454be197f7dac1f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_26429705ec7802a4410fde117dbad14e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6760ee61f70ee8088af837921ac1791d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-721 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-68 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
filingDate |
1995-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04c14c1dda93d32370ae612fb0a1b46b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7ac868335e9224a49e2ca9a840b7db4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_daa9ed0b7b53effc3621f0bc8e17b99f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df0239b1200519ff66410878851954c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c731f6b42c1acd4c4a5651f441787a78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45e228bb1293904ebf981fccefe7b1c5 |
publicationDate |
1996-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9613519-A1 |
titleOfInvention |
Activation of a human steroid receptor |
abstract |
Through the use of the novel receptor NER in a screening procedure, TOFA (5-tetradecyloxy)-2-furan-carboxylic acid) has been found to modulate other receptors and to be a potent potentiator of other drugs. TOFA activates the NER receptor. The NER receptor is a novel member of the steroid hormone receptor family and has been prepared by cDNA cloning from a human osteosarcoma SAOS-2/B10 cell library. Also disclosed is the complete sequence of human NER cDNA; a COS stable expression system; the expressed NER protein; and an assay using the COS expression system. In addition, the invention relates to a method for identifying functional ligands of the NER receptor. |
priorityDate |
1994-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |