| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed16992a03359c4e7b6adfa3ffcdbc88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4af2cdf6178ad5e09240bf3eb35ef509
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b3a40909619dee228f76bea5d3faf81 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-111 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1079
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1082
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1131
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6897
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
1995-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa671604a3402f08420f0c73de7e6231
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9643919b57900299aedb0d650dc53868
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81ca508133a694819d5707a99d37e749 |
| publicationDate |
1996-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9611211-A1 |
| titleOfInvention |
Selective inhibition of internally initiated rna translation |
| abstract |
A method to inhibit translation of an mRNA, which is intitiated at an internal ribosome entry site of the mRNA and requires binding of a protein factor to that site, is disclosed. The method comprises a step of providing, in an in vitro, or in vivo system that is capable of translating the mRNA, an inhibitory effective amount of a molecule that selectively binds to the protein factor, thereby preventing that factor from binding to the mRNA. The inhibitor molecule is an RNA oligonucleotide consisting of less than 35 nucleotides or a structural mimic of such an RNA oligonucleotide. Nucleotide sequences of such inhibitor RNA oligonucleotides include portions of the following sequences: the 60 nucleotide sequence of a yeast inhibitor RNA or of the sequence complementary to that yeast inhibitor RNA; nucleotides 186-220 of poliovirus (stem-loop D); nucleotides 578-618 of poliovirus (stem-loop G); nucleotides 260-415 of poliovirus (stem-loop E); nucleotides 448-556 of poliovirus (stemp-loop F); and the sequence of the internal ribosome entry site of the immunoglobulin heavy chain binding protein (Bip). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018144087-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0005366-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9961613-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1390392-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9937807-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-770432-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6171821-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4219709-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1390392-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9227956-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6291637-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9961613-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0005366-A2 |
| priorityDate |
1994-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |