| abstract |
A monoclonal antibody having high affinity and specificity to cardiac troponin I is described. The antibody was shown to have an epitope within the cardiac specific region on the N-terminus of the protein. This monoclonal antibody is especially useful as a reagent in a rapid format immunoassay system to identify blood, serum or plasma levels of cardiac troponin I. Such an immunoassay system can be used for diagnosing and quantifying myocardial necrosis and infarction. |