| abstract |
An imidazole derivative represented by general formula (I) or a salt thereof, having the effect of specifically inhibiting the growth of HIV as a pathogenic virus and being reduced in toxicity. In said formula R1 represents hydrogen, C¿1?-C20 alkyl, C2-C7 alkenyl, C4-C12 cycloalkylalkyl, etc.; R?2¿ represents C¿1?-C6 alkyl, C1-C6 acyl, hydroxy-iminomethyl, hydrazonomethyl or -(CH2)n-R?4 (R4¿ being halogeno, alkoxy, hydroxy, etc.; and n being an integer of 1 to 30); R3 represents substituted or unsubstituted C¿1?-C6 alkyl; X and Y represent each independently hydrogen, C1-C3 alkyl, halogeno or nitro; and Z represents S, SO, SO2 or CH2. |