abstract |
The proposed biologically compatible hydrogel is intended for use in the correction of cosmetic or functional defects (e.g., of the mammary glands, vocal cords, penis, etc., by endoprosthesis), in the creation of interstitial reservoirs of prolonged-action drugs, or for use as electroconductive immersion mediums and for the permanent packing of sinuses. The proposed hydrogel contains an acrylamide-based polymer obtained using a radical polymerisation initiator in apyrogenic water as the dispersion medium. In order to improve the flexibility, firmness and stability of bulk implants and thus improve their therapeutic and cosmetic effectiveness especially in endoprosthesis, the hydrogel contains cross-linked polyacrylamide obtained using a biologically compatible cross-linking agent, preferably methylene-bis-acrylamide, and preferably using a mixture of ammonium persulphate and tetramethylethylene diamine as the polymerisation initiator. The preferred concentration of this polymer in the hydrogel is between 3.5 and 9 % by weight. |