| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14d77f7a2f9bb70ba388c5edb6530d4e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d0ae570525665118e2f472088f75f42e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_857f8336175d4a3144facf2e9ad3998b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-975
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-811 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
1995-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d4066d7985851ea0fdd3822baab2fee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_921547b902d5866dad550602fa917b2e |
| publicationDate |
1996-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9604309-A1 |
| titleOfInvention |
Monoclonal antibodies specific for an epitope of a particular subclass or form of phosphorylated tau, hybridomas secreting them, antigen recognition of these antibodies and their applications |
| abstract |
The present invention relates to a monoclonal antibody which forms an immunological complex with a phosphorylated epitope of a particular subclass or form of phosphorylated tau protein without forming an immunological complex with (i) fetal tau or (ii) biopsy or autopsy derived brain material from patients having died or suffering from diseases in which NFT is not a pathological hallmark. The invention also relates to a process for diagnosing brain diseases involving monoclonal antibodies of the invention. The invention also relates to a region of the tau molecule which is specifically recognized by the monoclonal antibodies of the invention. The invention also relates to kinases or phosphorylases which specifically react with the epitope recognized by these monoclonal antibodies as well as to a method for screening compounds which interfere with the activity of these kinases and phosphorylases. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2298814-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9945393-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-772151-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7070943-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3792278-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6797478-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11365244-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0227017-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2040078-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104024274-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IL-263021-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8940272-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012049570-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9598484-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2794654-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7888050-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7442516-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6680173-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10196440-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0155725-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9605059-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9371376-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9745371-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10393759-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013096380-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3578567-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022144406-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10000559-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7387879-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0155725-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0123894-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11275092-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10766953-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1535930-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1535930-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8114617-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0014546-A1 |
| priorityDate |
1994-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |