http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9604007-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50eb752940fa4aa36756a6bc9f6f3504 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68c213ba9952360f439567152e047b18 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-185 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 |
| filingDate | 1995-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fd35ac10914364c5e82bb78d95507e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_810067bdea85cebd6f8125db79a0f66e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f0f5cb65b43ab8d53612d8ba29d4007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23640c9123ba7ddcdc99ab24dd0fafdc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fec534ba3b85806f548579f7bd9e01c |
| publicationDate | 1996-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9604007-A1 |
| titleOfInvention | Methods for treating addictive disorders |
| abstract | The present invention is broadly directed to treatment of an addictive disease or disorder. In particular, the invention relates to inhibiting or reversing the biochemical and neurophysiological changes that correlate with behavioral changes of addictive diseases or disorders. The method of the invention comprises administering to a subject suspected of suffering from an addictive disease or disorder an amount of brain-derived factor (BDNF) or neurotrophin-4 (NT-4), or both, effective to reverse behavioral changes that are associated with the addictive disease or disorder. In a specific example, administration of BDNF or NT-4 inhibits or reverses increased expression of tyrosine hydroxylase and glial ibrillary acidic protein in the ventral tegmental area of the brain, and inhibits or reverses increased levels of cyclic-AMP-dependent protein kinase activity in the nucleus accumbens. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0879048-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8309122-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8329216-B2 |
| priorityDate | 1994-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 383.