abstract |
Dammara compounds have immunosuppressant and anti-inflammatory activity and are useful as pharmaceuticals, particularly for use as immunosuppressant and anti-inflammatory agents. 17α dammara compounds are novel and are included per se, for example the compound of formula (IC) [(17α)-23-(E)-dammara-20,23-dien-3β,25-diol], which may be obtained from the flour of the shoots of the Palmyrah palm, Borassus flabellifer L. In addition processes for the synthesis of this and other dammara compounds and intermediates thereof are described. |