| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7aa001f3235c07b0298867908d45e21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_755aafba9ea5fd9bde0ec6286fe47e7f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e745d600af9abbbc306be67097b7d57c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-4088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-163
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B3-112 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B3-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
| filingDate |
1995-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ae014d0e41b3605ea837d89a0aa77b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_711ebd0ff9c60965fa8da3a64c78658e |
| publicationDate |
1996-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9603070-A1 |
| titleOfInvention |
Non-invasive method for diagnosing alzheimer's disease in a patient |
| abstract |
The present invention provides non-invasive methods for diagnosing Alzheimer's disease in a living human subject. One method employs a non-invasive automated apparatus which can continuously monitor pupil diameter size over time; repetitively measure pupil diameter size over time for a pre-chosen duration ranging from about less than 1 second to about 5 minutes; and cumulatively record size information as it is obtained over time. A second method employs an apparatus which can repetitively measure pupil constriction velocity for a pre-chosen duration both before and after stimulation by visible light. Both methods require the administration of at least one neural transmitter mediator to a targeted eye of the living subject in an amount insufficient to cause marked changes in pupil diameter size over time in a person who is not afflicted with Alzheimer's disease. The marked hypersensitivity of an Alzheimer's dementia patient to the administered neural transmitter mediator serves as the means for identifying individuals afflicted with Alzheimer's disease. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8911085-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5883691-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7670002-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3320841-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1127534-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0743041-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8534840-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6669651-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6024450-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8235526-B2 |
| priorityDate |
1994-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |