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filingDate 1995-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1c9282f113eac4de3b40cad496a96f2
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publicationDate 1996-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9601125-A1
titleOfInvention Use of insulin and igf-i
abstract The invention relates to the use of a combination of insulin and an Insulin-like growth factor I (IGF-I) in the manufacture of a medicament for counteracting a decrease in nitrogen balance and for counteracting a decrease in protein synthesis and which can be used for treatment of catabolism which is a protein catabolism due to glucocorticoid excess. The ratio of IGF-I to insulin in the medicament preferably ranges from 30:1 to 2:1, based on molecular weight. The medicament may be suitable for the treatment of patients with high serum level of IGFBP1 or other low molecular weight BPs.
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