| abstract |
An antibacterial containing a ketonitrile derivative represented by general formula (1) or a salt thereof as the active ingredient and having an excellent antibacterial activity against Gram-positive and Gram-negative bacteria, wherein R1 represents hydrogen or lower alkyl; R?2, R3, R4 and R5¿ represent each independently hydrogen, halogen, nitro, lower alkyl, lower alkoxy or (un)substituted phenoxy; X represents (un)substituted aromatic hydrocarbyl or (un)substituted heterocycle; Y represents (un)substituted aromatic hydrocarbyl, (un)substituted heterocycle, carbonyl substituted by (un)substituted aromatic hydrocarbyl, carbonyl substituted by (un)substituted heterocycle, or N,N-disubstituted carbamoyl. |