Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_29c8c50f3be68275baf0e7b3c8a2503f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3354657c7233a9ab4a856c2d0c1e70df http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec0024795f45a646ef64b3664ab8a26d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a71e58f25e39b21f25e64173bb0893a |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
filingDate |
1995-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f7011cac364d44329f99f2918ebd7e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d076351818cefaca2f0617e0cb3859b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6f0ba73759afa026e2fbc559f37ddda |
publicationDate |
1996-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9600231-A1 |
titleOfInvention |
Anti-sense oligonucleotides for aromatase inhibition |
abstract |
The invention concerns an anti-sense oligonucleotide which is suitable for use in inhibiting the expression of aromatase, the anti-sense oligonucleotide being obtained by the following steps: a) construction of anti-sense oligonucleotides along the whole length of coding and regulating zones of aromatase DNA and/or transcripts thereof, the anti-sense oligonucleotides overlapping each other, b) incubation of an aromatase-expressing cell with one or more of the anti-sense oligonucleotides from a) and c) analysis of the inhibition of aromatase expression in the usual way, as well as identification of the anti-sense oligonucleotide(s) responsible. The invention also concerns a method of preparing such an anti-sense oligonucleotide as well as its use. |
priorityDate |
1994-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |