| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a39b79bb469a9ffc7a21df51f703bbb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8405856a389cdfb6188fe67589ae560d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3830f35387a1c32061dea3ee310851
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69430a231e48b409fd0b97b4f2ac2dff |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-839 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-027 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
1995-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a364f8770aa644ce40babd452327cc40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab763113b18869c7fa8fb4d15ca9e6ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe986acdb08c6154380645ceb6ba955b |
| publicationDate |
1995-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9535366-A1 |
| titleOfInvention |
Animal model for alzheimer's disease |
| abstract |
Method of generating a non-human animal model having Aβ deposits in the brain of the animal by injecting an amount of human A68 protein sufficient to result in formation of the deposits and subsequently examining the animal for the formation of the deposits are disclosed. Non-human animal models characterized by the presence of Aβ deposits similar to those found in individuals with Alzheimer's disease are also disclosed. Methods of screening test compositions for prophylactic or therapeutic activity by generating a non-human animal model having Aβ deposits in its brain, treating the animal with the test composition and examining the animal for therapeutic or prophylactic effectiveness are also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150145201-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0149107-A1 |
| priorityDate |
1994-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |