Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f84747e8d08b1023763356d0e7d1db68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea701e837319b20c39cfdb21cb763a14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8c03150b3c8958d53f59fd87d12eff0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6582742e4bec2d62f0a2b1c1dfdc7c36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ebf36bcea0b82b1cfe93e338cb31dcad |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-685 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
filingDate |
1995-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3b25947ab5f362a58779b2a7ad30b53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0ef7ea90cb3129e5a26ed9e83b491e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4617c250f810a9b37eb0bfa6ef4a719 |
publicationDate |
1995-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9534288-A1 |
titleOfInvention |
Methods of treating hypertension and of improving impaired renal function |
abstract |
A method of treating hypertension and related symptoms thereof is described. A suspension of small, unilamellar vesicles composed primarily of phospholipids similar in nature to those of egg phosphatidylcholine is administered parenterally to a subject in need of such treatment repeatedly and over an extended period of time of at least several days, until a significant drop in blood pressure is observed. A method of improving renal function is also disclosed. In the treatment method, a suspension of liposomes is administered parenterally to a subject in need of such improvement repeatedly and over an extended period of time of at least several days, until a significant improvement in renal function is observed, as evidenced by an improvement in glomerular filtration rate characterized by a drop in plasma creatinine concentration of at least 10 percent. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0850047-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9326953-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0850047-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014517065-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014120181-A1 |
priorityDate |
1994-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |