| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a5e95156255d5fe8b2923c544786e176
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_54068d32f2a285519bc29a6fb92da650 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-265
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-197
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-192 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-197
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-192
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-265 |
| filingDate |
1995-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_266655c2fc0a7613fc691c8b5c84a25d |
| publicationDate |
1995-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9531192-A1 |
| titleOfInvention |
Method and use of agents to inhibit protein polymerization and methods of identifying these agents |
| abstract |
A method of inhibiting polymerization of target proteins by administration of compounds capable of inhibiting aggregation and subsequent transglutaminase-induced cross-linking of adjacent peptides of the target proteins is provided. These compounds are useful as antithrombotic agents and in the treatment of Alzheimer's disease. A method of screening and identifying compounds capable of inhibiting aggregation and subsequent transglutaminase-induced crosslinking of amyloid β peptide is also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10106570-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1539132-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9639194-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9932319-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7320988-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7652037-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012015912-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7030133-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1539132-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5849711-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9198886-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6337350-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6605642-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0059875-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0059875-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9840480-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02074221-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8124655-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6787566-B2 |
| priorityDate |
1994-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |