| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39a61dd98bb2a18d85b4b77743ab8271
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d3a8178dff6533845774511698b775f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a709a56cfb238f1572b4014f37a0931f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-235
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-325
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-14 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-235 |
| filingDate |
1995-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60065148a4717192391687365689e46e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24bc0f4b1b2b3db9877c43a3bfd86610
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_301a7a65205baa25bed3363555b2ad06 |
| publicationDate |
1995-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9529934-A1 |
| titleOfInvention |
Method of separating protective components of bordetella pertussis |
| abstract |
To provide a method of efficiently separating protective components of Bordetella pertussis. On the basis of differences in adsorbability to calcium phosphate gel formed by adding calcium ions to a Bordetella pertussis culture in the presence of excess phosphate ions, protective components of Bordetella pertussis are separated from the Bordetella pertussis culture. Traditionally, protective components of Bordetella pertussis have been separated using different purification methods for the respective components. According to the present invention, the use of the same means of purification for all subject components makes it possible to purify each component with high efficiency and high recovery rate, an aspect very advantageous for industrial production. It is also possible to efficiently produce an improved purified pertussis component vaccine comprising an effective combination of pertussis filamentous hemagglutinin (FHA), pertactin (PRN, 69K-OMP), pertussis fimbriae (FIM) and pertussis toxin (PT). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1405643-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6399076-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1393744-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9634623-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1234579-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1234580-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010131111-A1 |
| priorityDate |
1994-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |