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filingDate 1995-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ae2c37a62ccae0989a0439fbe1f6a2b
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publicationDate 1995-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9528426-A3
titleOfInvention Peptides for reducing or inhibiting bone resorption, angiogenesis and restenosis
abstract The present invention provides Arg-Gly-Asp peptides that can alter the binding of osteoclasts to a matrix such as bone or can selectively alter integrin receptor binding. The invention also provides methods of using the Arg-Gly-Asp peptides to alter αVβ3 integrin receptor-mediated binding of a cell such as an osteoclast, endothelial cell or smooth muscle cell to a matrix. The invention further provides methods for ameliorating the severity of a pathology characterized, in part, by an undesirable level of bone resorption, angiogenesis or restenosis in a subject.
priorityDate 1994-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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