| abstract |
This invention provides compounds of chemical formula (I) or their pharmaceutically acceptable salts, wherein R is hydrogen or chloro. Also, the present invention provides a process for the production of the compound of formula (I), which comprises cultivating a microorganism having the identifying characteristics of Aspergillus fischeri var. thermomutatus ATCC 18618 or the like, and then isolating the compound of formula (I) from the fermentation broth. The pyrrolobenzoxazine compounds of formula (I) of this invention have broad antiparasitic activity, and thus are useful as antiparasitic agents, especially as anthelmintics. |