http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9518133-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a717ea5b2ac78ac329ab3a9659d834d2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 |
| filingDate | 1994-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c5eb4bcecdf271bab9d68c0fa709b0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_438539495a679254d9aa676aa162d5c8 |
| publicationDate | 1995-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9518133-A1 |
| titleOfInvention | Amino alkanoic esters of rapamycin |
| abstract | This invention provides a compound of structure (I), wherein R?1 and R2¿ are each, independently, hydrogen or (1); R3 is -(CH¿2?)qCO2R?6; R4¿ is hydrogen, alkyl, or arylalkyl; R5 is hydrogen or COOR7; R6 is hydrogen, alkyl, alkenyl, arylalkyl, fluorenylmethyl, or phenyl which is optionally substituted; R7 is alkyl, alkenyl, arylalkyl, fluorenylmethyl, or phenyl which is optionally substituted; m is 0-4; n is 0-4; p is 1-2; q is 0-4; wherein R3, R4, m, and n are independent in each of the (2) subunits when p=2; with the proviso that R?1 and R2¿ are not both hydrogen; and further provided that if R5 is CO¿2R?7, then R6 is hydrogen; and still further provided that if R6 is not hydrogen, then R5 is hydrogen; or a pharmaceutically acceptable salt thereof which is useful as an immunosuppressive, antiinflammatory, antifungal, antiproliferative, and antitumor agent. |
| priorityDate | 1993-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 176.