| abstract |
DNA encoding a novel human β2 integrin α subunit polypeptide, designated αd, is disclosed along with methods and materials for production of the same by recombinant procedures. Fusion proteins are also disclosed which include extracellular αd protein fragments, αd I domain fragments or full length αd polypeptides and human immunoglobulin constant regions. Binding molecules specific for αd are also disclosed as useful for modulating the biological activities of αd. DNA from other species which show homology to human αd encoding sequences are also disclosed. |