abstract |
New pyridazino[4',5':3,4]pyrrolo-[2,1-a]isoquinolines have formula (I), in which X stands for O, S or NHO. These new compounds have precious therapeutic properties. They are useful as heart and brain protective agents, as therapeutic agents for chronic inflammatory processes, as antiproliferative agents and as therapeutic agents for ulcerative colitis and Crohn's disease. |