| abstract |
Disclosed are compounds of formula (I), or a pharmaceutically acceptable salt or solvate thereof, wherein: R3 is alkyl, alkenyl, alkynyl, aryl, alkaryl, aralkyl, cycloalkyl, acyloxymethyl, alkoxy, alkoxymethyl, or alkyl substituted with cycloalkyl; R4 is H, alkyl, alkenyl, alkoxy, or -OH. Also disclosed are pharmaceutical compositions containing compounds of formula (I), methods for inhibiting tumor necrosis factor-α and methods for treating septic shock, inflammation, or allergic disease by administering a compound of formula (I). |