| abstract |
The invention concerns highly active sulphonyl urea preparations exhibiting rapid or controlled release of the active substance for use in the treatment of diabetes. Covered are liquid and rapid-release or controlled-release solid pharmaceutical preparations characterized in that they contain one or more sulphonyl urea derivative(s) as the active substance(s), alcohol, one or more polyol(s), with the exception of polyethylene glycol, and/or more sugar alcohol(s), previously dissolved in water or an alcohol/water mixture, an alkaline-reacting substance and, optionally, suitable pharmaceutically tolerated auxiliaries and flavours plus, optionally, other pharmaceutically active substances. The invention also concerns a method of producing such preparations and their use in the treatment of the illness diabetes mellitus. |