http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9510303-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6420d04b0d68f339771080e32bd0fbc9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e7eb1e8e0550dadfe0bb9183116962f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-4241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-065 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-06 |
| filingDate | 1994-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44053f7eb4bd5b990d108a48188ae5be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f49dbee2aeef6bc4d8806fc5930a04b8 |
| publicationDate | 1995-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9510303-A1 |
| titleOfInvention | Use of anti-idiotypic antibodies to prevent hyperacute rejection of xenografts |
| abstract | Antibodies directed against idiotypes on naturally occurring human anti-animal antibodies are disclosed for use in inhibiting xenograft rejection in human patients. An effective quantity of these anti-idiotypic antibodies is injected into the actual or potential xenograft recipient in order to bind to the idiotypes expressed on anti-animal antibodies as well as subpopulations of B lymphocytes, to inhibit hyperacute rejection of transplanted animal tissues or organs by the human patient. Alternatively, anti-idiotypic antibodies are used in the form of immunoaffinity columns to deplete anti-animal antibodies from the recipient's serum. Methods of making mouse monoclonal, mouse recombinant, and human recombinant anti-idiotypic antibodies are described, as well as immunoaffinity columns containing immobilized anti-idiotypic antibodies. A method and means for assessing the expected character and severity of a patient's rejection response to transplanted animal tissues is described, as well as methods of identification, isolation and suppression of lymphocytes bearing anti-animal idiotypes. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0689597-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005061546-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9534581-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9420770-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1544215-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0689597-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7892542-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5785966-A |
| priorityDate | 1993-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.