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filingDate 1994-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1995-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9509249-A1
titleOfInvention Oral vaccination of mammals
abstract Oral anti-rabbies vaccines that comprise at least 100 νg of an isolated rabies glycoprotein G that is produced in eukaryotic cells and methods of immunizing mammals against rabies infection which comprise the step of orally administering to the mammal, such oral anti-rabies vaccine are disclosed. Chimeric proteins are disclosed. Orally active vaccines for immunizing a mammal against a pathogen infection comprising chimeric proteins and methods of using the same are disclosed. Oral anti-pathogen vaccines that comprise at least 100 νg of an isolated rabies glycoprotein G and either an isolated pathogen antigen or a peptide which comprises a neutralizing epitope of a pathogen antigen and methods of using the same are disclosed.
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