http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9508558-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94ff2d78578d95d1e8d3a2233c76188d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0011 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 |
| filingDate | 1994-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3eb3cf1e6a397e8680b27890ad6d5f25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb40b469dbcbdf0d334672f29a5b73ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51e89757e77668fdc9766f2e4fab66d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59413601e7adb777b9cd33ebe8f77eaf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a2559894c01115863e408e79fda3643 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09cfdcfe68a289e6143c46c8551c57a4 |
| publicationDate | 1995-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9508558-A1 |
| titleOfInvention | Novel deoxy and oxygen-substituted sugar-containing 14-aminosteroid compounds |
| abstract | Deoxy and oxygen-substituted sugar-containing 14-aminosteroid compounds and the pharmaceutically acceptable acid salts or esters thereof of general formula (I), wherein a) R1 is (i) COOR5, where R5 is a 1-6 carbon lower alkyl group; a 1-6 carbon lower alkyl group substituted by an amino group; an arylalkyl or heteroarylalkyl group or a carbocyclic ring, or (ii) CHR6OH, where R6 is a hydrogen atom or a 1-6 carbon lower alkyl group, or (iii) COR''', where R''' is hydrogen; 1-6 carbon lower alkyl; 1-6 carbon lower alkyl substituted amino; amino or dialkylamino, and b) R2 is -NR7R8; where R7 and R8, which may be the same or different, are hydrogen atoms or 1-6 carbon lower alkyl group, and c) R3 is (i) a deoxy or oxygen-substituted monosaccharide sugar residue, (II) wherein R9a, R9, R10, and R10a, which may be the same or different, are 1-6 carbon lower alkyl; hydrogen; hydroxy; fluorine; alkoxy; acetoxy; arylalkyloxy; or benzoxy; R11 is 1-6 carbon lower alkyl; hydrogen; hydroxy; fluorine; benzoxy; arylalkyloxy; heteroarylalkyloxy; acetoxy or alkoxy; wherein further when R5 is 1-6 carbon lower alkyl; either R9, R10, or R11 cannot be hydroxy or acetoxy; further provided that when R9a is hydrogen and R10a is hydrogen and R9 is hydrogen; hydroxy or acetoxy; and R11 is hydroxy; acetoxy or alkoxy; R10 cannot be hydroxy or acetoxy; and R12 is methyl; acetoxymethyl or hydroxymethyl; t can be a single or double bond, or (ii) a deoxy or oxygen-substituted monosaccharide sugar residue, (III) wherein R11 is arylalkyloxy; heteroarylalkyloxy or 1-6 carbon lower alkyl substituted oxosilane and R12 is methyl, and d) R4 is (i) OH, or (ii) H, or (iii) OR13, where R13 is a monosaccharide sugar residue; acetoxy; benzoxy; arylalkyl or heteroarylalkyl, and e) Z is (i) -CH-, where a and b are single bonds, or (ii) =C, where either a or b is a double bond. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0721459-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9748401-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1955700-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7462605-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5972239-A |
| priorityDate | 1993-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 647.