| abstract |
This invention relates to methods for the generation of nucleic acid compositions for the treatment of conditions affecting the skin and related structures. Nucleic acid molecules such as ribozymes which specifically interact with and modify the expression of cutaneous biological molecules can be developed as effective, safe, therapeutic or cosmetic reagents. These ribozymes can be used for the treatment of disorders that include: aging, environmental insult, inflammation, and genetic predisposition. The methods used to develop these reagents are described. |