| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_45a3703d03a4b21be619937f5ad63b8b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7156 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate |
1994-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_269b3be06e2e22ed52f9fb9a989fe495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a70380512dd97d2943e8a3c862ee5c00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bcccb1d73dddc3b1aa132c0e0ed726a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d7ebade0a881cf128f6f85c3d56b1ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_250f9d91d6d69cb1f91dc85613325177
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8eef564c6e3f37adfeb79ac487af4d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3be3546182301310df959d4f10c65383
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_683ed1467b09f7e0d9056edd2e63b705 |
| publicationDate |
1995-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9505847-A1 |
| titleOfInvention |
Accessory factor function for interferon gamma and its receptor |
| abstract |
This invention relates (a) to a 540 kb YAC which encodes the necessary species-specific factor(s) and is able to substitute for human Chromosome 21 to reconstitute the Hu-IFN-gamma receptor-mediated induction of class I HLA antigens; (b) to the construction of a plasmid to integrate the selective marker for antibiotic G418 resistance into YACs and to delete some of the human DNA fragments from YACs in order to facilitate the manipulation of human genomic DNA in yeast artificial chromosome (YAC) clones; (c) to two fragmentation vectors, pSE1 and pSE2, which contain a neomycin resistance and URA3 gene, developed for targeting yeast artificial chromosomes (YACs) containing human genomic DNA; (d) to a chromosomal fragmentation procedure employed to produce a deletion set of yeast artificial chromosomes (YACs) from a parental YAC (GART D142H8) known to map to Chromosome 21q and to encode the human interferon-gamma receptor (Hu-IFN-gamma R) accessory factor gene as well as the phosphoribosylglycinamide formyltransferase (GART) gene; and (e) to the isolation of cDNA clones that encode the necessary species-specific factor and that are able to substitute for human Chromosome 21 to reconstitute the Hu-IFN-gamma receptor-mediated induction of class I HLA antigens. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6586228-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9516036-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7608430-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007018879-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007018879-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7342103-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9946379-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7812126-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2527456-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9516036-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9966059-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9946379-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010051288-A1 |
| priorityDate |
1993-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |