abstract |
Peptide-based compounds containing four invariant cysteine residues which have been optionally oxidized to contain two intramolecular disulfide bonds, or modified forms where the cysteines are replaced, are useful as preservatives and in preventing, treating or ameliorating viral or microbial infection in animals and plants, and in inactivating endotoxin. Exemplary peptides include the following in purified and isolated form: RGGRLCYCRRRFCVCVGR, RGGRLCYCRRRFCICV, RGGGLCYCRRRFCVCVGR, and RGGRLCYCRGWICFCVGR. |