abstract |
A method of preventing or treating hypoxia-associated ocular complications in a host in need of such prevention or treatment which comprises administering to the eye of the host a prophylactically or therapeutically effective amount of at least two agents selected from the group consisting of an aqueous soluble, solution-stable heme oxygenase inducer, a membrane-permeable anti-acidosis buffer, and an osmoprotectant, as well as an aqueous ophthalmic composition useful therefor. |