| abstract |
Boron neutron capture therapy can utilize XyB20H17L where X is an alkali metal, y is 1 to 4, and L is a two electron donor such as NH3, and Na2B10H9NCO, among others. These borane salts may be used free or encapsulated in liposomes. Liposomes may have embedded within their bilayers carboranes to increase the amount of delivered 10B and/or to increase the tumor specificity of the liposome. |