| abstract |
A 1-(2-benzimidazolyl)-1,5-diazacyclooctane derivative represented by general formula (I) (wherein X represents hydrogen or halogen; Y represents a single bond, C1-C6 linear or branched alkylene or C2-C6 linear or branched alkenylene; and R represents hydrogen or C1-C6 linear or branched alkyl) and a pharmacologically acceptable salt thereof. This compound is a histamine H1 receptor antagonist which can be topically administered via inhalation as a remedy for bronchial asthma. |