abstract |
Use of a calcium carbonate based porous material as support for at least one growth factor in the preparation of a bioabsorbable implant to be placed in a living animal organism, in particular a vertebrate. In the case of an osteoinductive growth factor, the implant may be a bone filler or may be placed in a conjunctive tissue where it will generate bone tissue for use as an autograft. In the case of a non-osteoinductive growth factor, the implant may be used to grow cells in vivo. It is, for example, possible to use a hollow implant into which modified autologous cells are introduced, particularly by gene insertion. Once in place, the implant becomes an organoid correcting, for example, a dysfunction of genetic origin. |