Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_916075766043ce900399a4c2eee9f054 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-968 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-918 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-12 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-20 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-20 |
filingDate |
1994-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_faa6db45a0e802b7d03ff67edd11ca80 |
publicationDate |
1994-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9425623-A1 |
titleOfInvention |
Method of identifying compounds that modulate myocardial calcium-independent phospholipase a2 activity |
abstract |
A method of identifying compounds that modulate the activity of myocardial calcium-independent phospholipase A2 is disclosed. In a test assay of the method of the invention, myocardial calcium-independent phospholipase A2 40kDa catalytic subunit, 85kDa phosphofructokinase isoform, ATP, a substrate and a test compound are combined and the myocardial calcium-independent phospholipase A2 activity is determined. The level of activity observed in the test assay is compared to the level of activity generated from a control assay which is similar to the test assay but which does not include the test compound. Essentially pure myocardial calcium-independent phospholipase A2 85kDa phosphofructokinase isoform is also disclosed. |
priorityDate |
1993-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |