| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43e202cbfea2eadc4a48f83f292b80dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae126216c3e0066dfb617caeb4f628e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_74b334abea11b7edb7fd67f1ed91ce56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a5e95156255d5fe8b2923c544786e176 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1138 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate |
1994-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5256fb554fab2e7ad52ef70a96356fee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d59f2928bc524cb2c0999cbc40262615
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c17fa5071a6840a935469da8ff6a7c0 |
| publicationDate |
1994-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9422486-A1 |
| titleOfInvention |
Method of inhibiting the proliferation and causing the differentiation of cells with igf-1 receptor antisense oligonucleotides |
| abstract |
A method of inhibiting the proliferation and causing the differentiation of undifferentiated cells comprising contacting the undifferentiated cells with an effective amount of an antisense oligonucleotide having a sequence which is complementary to a region of the IGF-1 receptor RNA. The sequence of the antisense oligonucleotide is selected from an oligodeoxynucleotide sequence complementary to codons -29 to -24 of the signal sequence of the IGF-1 receptor and an oligoribonucleotide sequence complementary to codons 1 to 309 of the sequence of the IGF-1 receptor. The oligoribonucleotide sequence may be provided by an expression vector. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6084085-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110273001-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-692278-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9718241-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9822579-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9923259-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5929040-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9610401-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6900186-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1597366-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6284741-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8217017-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7468356-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1597366-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9601636-A1 |
| priorityDate |
1993-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |