abstract |
Immunomodulatory macrocyclic compounds having formula (I) and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, where R?8 and R9¿ are selected such that one of R?8 and R9¿ is hydrogen and the other is -S(O)¿s?-heterocyclic, as well as pharmaceutical compositions containing such compounds and therapeutic methods of their use. |