| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa48a431ce250933eb0fdd7a1caf3f30 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-2982 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6933
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5138
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6931
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-18 |
| filingDate |
1994-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b4eb8baccf89378619d80e70f6e4785
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef1b923e5fd6586bcf9e5d6b25474a9a |
| publicationDate |
1994-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9418955-A1 |
| titleOfInvention |
Compositions for oral delivery of active agents |
| abstract |
Compositions and methods for the oral administration of drugs and other active agents are provided. The compositions comprise an active agent carrier particle attached to a binding moiety which binds specifically to a target molecule present on the surface of a mammalian enterocyte. The binding moiety binds to the target molecule with a binding affinity or avidity sufficient to initiate endocytosis or phagocytosis of particulate active agent carrier so that the carrier will be absorbed by the enterocyte. The active agent will then be released from the carrier to the host's systemic circulation. In this way, degradation of degradation-sensitive drugs, such as polypeptides, in the intestines can be avoided while absorption of proteins and polypeptides from the intestinal tract is increased. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9613250-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0981649-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9620698-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9620698-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0981649-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6143037-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017175068-A1 |
| priorityDate |
1993-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |