| abstract |
Implantable artificial organs are disclosed for delivery of a biological agent from implanted cells placed within the body cavity of a subject. The cells (32) are maintained within a selectively permeable membrane (22), which permits the movement of the agent therethrough while excluding white blood cells (immunocytes), antibodies and other detrimental agents present in the environment of use from gaining access to the cells. The selectively permeable membrane is completely enclosed by a perforated housing (12) which protects the membrane from breakage and permits body fluids to be in close contact with the membrane. Implantable artificial organs are disclosed, all of which may be retrieved from the subject, replaced or recharged and reimplanted. |