| abstract |
Nanocapsules typically having a diameter in the range 150-400 nm are provided and consist of a phase enclosed in a polymeric shell formed of a network of polymers. The nanocapsules, can be used to encapsulate a wide range of water soluble active agents in high yield for delivery to a target system or locus, for example, drugs for use in therapy or prophylaxis. The nanocapsules can be formed by interfacial polymerisation of alkyl-2-cyanoacrylates in a two phase system consisting of immiscible water soluble polymers under polymerisation initiating conditions, resulting in encapsulation of the active agent within a polyalkylcyanoacrylate shell. |