| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a69996870471830a05654231bec9655 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1138
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
| filingDate |
1993-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b526189de9339f7c3aa037088e39176b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a33ace49106279c24036ac4c797a28b6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c76714a4b2e9a491a18ae4267cfa4314 |
| publicationDate |
1994-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9415945-A1 |
| titleOfInvention |
Antisense molecules directed against a fibroflast growth factor receptor gene family |
| abstract |
The present invention is directed to a polynucleotide of about 10 to about 50 nucleic acid bases in length, which polynucleotide hybridizes to the gene encoding fibroblast growth factor receptor. The present invention is also directed to a pharmaceutical composition comprising the above polynucleotide dissolved or dispersed in a physiologically tolerable diluent. The present invention is further directed to a process for inhibiting vascular smooth muscle cell proliferation (figs. 1 and 2), a process for treating vascular smooth muscle cell proliferation (figs. 3 and 4), and a process for treating a disease state involving vascular smooth muscle cell proliferation (figs. 3 and 4), all of which processes comprise contacting vascular smooth muscle cells or administering an effective amount of a polynucleotide of about 10 to about 50 nucleic acid bases in length, said polynucleotide hybridizing to the gene for fibroblast growth factor receptor. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8486904-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8933213-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9804686-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9804686-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5783683-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6380171-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0871494-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8895529-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010292140-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0871494-A1 |
| priorityDate |
1992-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |