| abstract |
Mammalian purified nucleic acids and proteins encoding mucosal addressins are provided. The proteins, nucleic acids and fragments thereof serve a variety of purposes in modulating leukocyte mucosal tissue homing interactions. In addition, the protein fragments may serve as antigens to produce antibodies specific for particular domains of the mucosal addressin, while the nucleic acids may be used as probes, for antisense preparation, for introduction into hosts which may be allogeneic or xenogeneic to the DNA source for expression of the protein, and the like. |