| abstract |
A benzanilide derivative represented by general formula (I) or a pharmaceutically acceptable salt thereof, useful for preventing or treating cardiac insuffiency, hyponatremia, syndrome of inappropriate secretion of antidiuretic hormone (SIADH), hypertension, renal insufficiency, edema, water metabolism disorder, and so forth based on arginine vasopressin receptor antagonism. In formula (I), R represents optionally halogenated lower alkyl, hydroxy, lower alkoxy, nitro, amino, mono- or di(lower alkyl)amino, or lower alkanoylamino. |