| abstract |
A method of hydrating mucous secretions in the lungs of a subject in need of such treatment is disclosed. The method comprises administering to the lungs of the subject a uridine triphosphate such as uridine 5'-triphosphate (UTP) or uridine 5'-O-(3-thiotriphosphate) (UTPĪ·S) in an amount effective to hydrate lung mucous secretions. The method is useful for treating patients afflicted with cystic fibrosis. Pharmaceutical formulations and methods of making the same are also disclosed. |