| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f7db878830ac8b877d3168c2ea10bc01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa48a431ce250933eb0fdd7a1caf3f30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_489bb78f43f7da8fa9903c7986dee643
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae8a7de23de8d53d4df0617afe00b359 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-585
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7084 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 |
| filingDate |
1993-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f8c642db2fb6c9a6fdbf47f51aedaef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5ca18b40dd262b06b069f849a28c32e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1363c5764bbd86ed1f76b1fa859c2fbb |
| publicationDate |
1994-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9408572-A1 |
| titleOfInvention |
Delayed onset transdermal delivery device |
| abstract |
The present invention is directed to a transdermal delivery device (10) for the controlled release of a drug or other therapeutic agent to skin or mucosa and adapted to delay the onset of therapeutic agent delivery at a therapeutically effective rate for a predetermined time after placement of the device onto the skin or mucosa. The device comprises a nonaqueous reservoir (104) which contains a therapeutic agent in complexation with an ion-exchange resin and also contains an activating agent, the reservoir having a surface through which the therapeutic agent is released to the skin or mucosa; and a rate-controlling membrane (106) disposed between the skin or mucosa and the releasing surface of the reservoir (104) for controlling the rate at which water is absorbed into the reservoir, the rate-controlling membrane (106) being substantially free of therapeutic agent prior to placement of the device onto the skin or mucosa. The present invention has the additional advantage of providing the therapeutic agent in a stable form prior to placement on the skin or mucosa as well as in a form suitable for absorption after such placement. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006081518-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005053691-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005053691-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9727844-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8741935-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6254883-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006081518-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1549633-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1549633-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9801408-B2 |
| priorityDate |
1992-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |