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http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe544f32673e077f6336b28eb6193731
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-78
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37
filingDate 1993-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e110640fcddadf15c6fc8231fcc3ea7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fb19f9d631ee679eb9f758e2d41b597
publicationDate 1994-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9405806-A1
titleOfInvention Method and product for diagnosis of collagen tissue destructive diseases such as periodontitis
abstract A method and product for the diagnosis of collagen tissue destructive diseases, such as periodontitis. A method includes collecting a sample of extracellular fluid from a potentially diseased site of a mammal. It is ascertained whether an amount of collagen-destructive enzyme in an active form is present in the sample in excess of a pre-determined threshold amount, such presence indicating the likely diseased condition of the site. The enzyme may be active gelatinase or active collagenase. Examples involving periodontitis and the use of a mouth rinse for collecting the sample are given. A capsule, being of collagen (or gelatin) is described. The capsule contains a colored substance and a wall of such thickness that when the capsule is exposed to a sample containing active collagenase (or active gelatinase) exceeding the threshold amount, degradation of the wall occurs to relase the dye from the capsule to indicate the presence of the disease at the site from which the sample was collected.
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priorityDate 1992-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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