http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9404677-A1

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filingDate 1993-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06ee9854c39bf9023ec88be1a99b7ce5
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publicationDate 1994-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9404677-A1
titleOfInvention The use of cd4 plasma membrane vesicles (pmv) as a therapeutic agent for aids
abstract This invention relates to a method for preparing recombinant protein-associated lipid vesicles derived from nucleated cell plasma membranes. In one embodiment of the invention plasma membrane vesicles are prepared that contain CD4 protein on their surface in the correct orientation. The vesicles have the improved ability to inhibit HIV-1 infectivity and syncytia formation over what is available in the art. In another preferred embodiment of the invention, the CD4-associated plasma membrane vesicles are used to target a medicament to HIV-1 infected cells.
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priorityDate 1992-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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