Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70514 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
filingDate |
1993-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06ee9854c39bf9023ec88be1a99b7ce5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b02bfaf51ff226417a4e03a62a327c18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5e696a5e5853deceac5b53e15fbd58a |
publicationDate |
1994-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9404677-A1 |
titleOfInvention |
The use of cd4 plasma membrane vesicles (pmv) as a therapeutic agent for aids |
abstract |
This invention relates to a method for preparing recombinant protein-associated lipid vesicles derived from nucleated cell plasma membranes. In one embodiment of the invention plasma membrane vesicles are prepared that contain CD4 protein on their surface in the correct orientation. The vesicles have the improved ability to inhibit HIV-1 infectivity and syncytia formation over what is available in the art. In another preferred embodiment of the invention, the CD4-associated plasma membrane vesicles are used to target a medicament to HIV-1 infected cells. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6916478-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9705899-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9705899-A3 |
priorityDate |
1992-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |