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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7f871411f032ed0fb0e077a4ae2816f
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-52
classificationIPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52
filingDate 1993-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca213f49f43fc6e0547dc1d66ee267b0
publicationDate 1994-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9404181-A1
titleOfInvention Heparin neutralization with multimeric peptides
abstract The invention features a peptide which is capable of neutralizing the anticoagulant effects of heparin, and which has the sequence Y X1 X2 Y X3 X4 X5 Y X6 X7 Y, wherein (a) each Y, independently, is selected from the group consisting of leucine, isoleucine, valine, phenylalanine, tyrosine and tryptophan, and (b) each X, independently, is selected from the group consisting of alanine, arginine, asparagine, cysteine, glutamine, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, serine, threonine, tryptophan, tyrosine, and valine. Methods for neutralizing the anticoagulant effects of heparin in a mammal using the peptide of the invention are also claimed.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2448717-C1
priorityDate 1992-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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